What is the best mouse for wrist pain and office work?

Top pick: Logitech Lift Vertical Ergonomic Mouse for most office workers with wrist discomfort. Its vertical shape encourages a more neutral hand position, it is compact enough for many desks, and it has the everyday office features most people need.

If you have larger hands or want a more premium feel, choose the Logitech MX Vertical. If wrist movement itself is the problem, consider a trackball like the Kensington Expert Mouse, because your hand can stay mostly still while your fingers move the cursor.

Important: no mouse can guarantee relief from wrist pain. Pair the mouse with a neutral keyboard position, relaxed shoulders, forearm support, lower pointer sensitivity if you over-grip, and regular breaks. If you have numbness, tingling, weakness, or persistent pain, check with a clinician or ergonomics professional.